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PI: Disterhoft, Wang
Summary:
What does the development of memory formation look like and what is the nature of the interactions that exist between the hippocampus and cortical regions to enable information storage? Does the rapid acquisition of a memory encompass the same neural network as one that is acquired at a normal pace? The acquisition of memory is initially dependent on the hippocampus but the long-term storage of memory, termed consolidation, likely resides in the neocortex in a single area or network of regions. Because of the likely neural distribution of a consolidated memory in the neocortex, it is favorable to employ methods that simultaneously examine the entire brain. The goal of the proposed research is to determine how the gradual process of consolidation is incorporated in the brain and how factors involved in the acquisition phase influence the consolidated neural network.
Funding: